Swede Johan Carlsson fired in a pacesetting six-under 66 in the first round of the competition on Thursday.
The 30-year-old picked up five strokes in a blistering outward half of 30 before three back-nine birdies were partially offset by bogeys at the 10th and 18th.
While Carlsson was flying high at the top of the leaderboard, world No9 Justin Rose had to settle for a 72 and fellow Englishman Ian Poulter ballooned to a 76.
The fifth-ranked Henrik Stenson was handily placed on 68, one behind Italy’s Francesco Molinari, Kiradech Aphibarnrat of Thailand and Scott Jamieson of Scotland.
Keep up with all the action from the second round on Friday with our live updates from Wentworth
BWM PGA Championship 2017 latest updates
6.30pm: WOW! Justin Rose has hit an eagle on the final hole to make the cut.
The Olympic champion was in real danger of missing out after the second round until he pulled off a brilliant final hole.
Rose will now go into the third day two over par.
6.05pm: Ian Poulter admitted he would be wary of attending the FA Cup final between his beloved Arsenal and Chelsea in the wake of Monday’s terrorist attack in Manchester.
Poulter had hoped to be in contention for a first victory since 2012 in the BMW PGA Championship, which would have meant a late tee time and only being able to watch the final on television.
Poulter labelled his putting « pathetic » following a second round of 69 which saw him finish eight shots off the halfway lead, the 41-year-old was not certain he would use his early start on Saturday to make a last-minute trip to Wembley.
« I had really good opportunities to birdie all the way back into the clubhouse and I didn’t do it, » Poulter said after a round containing 16 pars, one birdie and an eagle on the 12th.
« I could have given myself a lie-in (on Saturday). Obviously going to have to get up at five in the morning, but the plus is I’ll be able to watch Arsenal beat Chelsea. »
6pm: Francesco Molinari has stormed to the top of the leaderboard with birdies on the final two holes.
He joines Scott Jamieson and Thomas Pieters at seven under.
5.45pm: Justin Rose has got two holes to save his weekend. The Brit is currently 4 over and in serious danger of missing the cut.
Scott Jamieson and Thomas Pieters hold a joint-lead but Francesco Molinari is not far behind.
5pm: Scott Jamieson has put himself in pole position by shooting a two under to go joint-level with Thomas Pieters.
Pieters shot three under, while the biggest move was Maximillian Kieffer who went four under to move up to third.
Lee Westwood has also had a good day shooting three under to sit joint fifth on five under.
Justin Rose, though, is in big trouble and faces missing the cut – currently at four over – as his rounds comes to its finale.
2pm: Saturday is traditionally moving day but it looks like there are plenty pulling the trigger early at Wentworth today in glorious sunshine and good scoring conditions.
Belgian Thomas Pieters finished fourth at the Masters earlier this year and has continued his good form.
He shot 68 yesterday and 69 today, leading in the clubhouse on seven under par.
Overnight leader Carlsson is yet to go out but the low rounds of the day so far are 68s from Germany’s Maximilian Kieffer and ever-popular Andrew Johnston – or Beef, as he is better known.